TB Vaccine PreClinical Pipeline – Sortable

Use this tool to filter vaccine candidates by phases, vaccine platform, target population(s), indication(s), animal models, and immunological information. A candidate may not appear in the filters on this page if the sponsor or developer has not submitted this information for inclusion.

Click on the candidate name for more information on the candidate and clinical trial information.

If you would like to submit a vaccine candidate for inclusion in the pipeline or update information for a vaccine candidate, please fill out the TB vaccine candidate submission form.

For more information about this Pipeline, please review the Terms of the TB Vaccine Pipeline.

Phases*

Type of Vaccine

Target Route of Administration

Animal Models

Target Population(s)

Immunological Response

Trained Immunity

Immune Tissue Localizations

Primary Indication(s)

Additional Indication(s)

TBvac-1, TBvac-2, TBvac-10


Univ of Minn

BCG-EVs


NIID, Japan Inst for Health Sec, TBVI, Niigata Univ, Osaka Met Univ

Tri:ChAd:TB


McMaster Univ

PNx6


James Cook Univ.

MtbΔfbpA


Univ Texas Rio Grande Valley, Texas Tech Univ, Houston Methodist Res Inst

SeV986A


Shanghai Public Health Clinical Center

mRNA-Rv1387-Rv0287-Rv1788


Harvard Med School

rBCG-LTAK63


Instituto Butantan

ChAdOx1.5Ag/MVA.5Ag


Univ Oxford

Spore-FP1


St George's Univ London, Sporegen LTD

MtbDsigH


Tulane Univ & Texas Biomed Res Inst, NIH, BMGF

AY035


Anyong Dingye Biotechnology Ltd.

Lm::Mtb9Ag


UCLA

BCG::ESAT6-PE25SS


James Cook Univ.

Mycobacterium microti ATCC 35782


Institut Pasteur Paris

BCG w/MK-2206


Institut Pasteur de Tunis, THSTI

BCG::ESX-1Mmar


Institut Pasteur Paris

BCGΔBCG1419c


CIATEJ

Spray Dried ID93+GLA-SE


AAHI, NIAID

The Preclinical Pipeline includes TB vaccine candidates that have been submitted to WGNV by the vaccine developer. It is not exhaustive. To submit a TB vaccine candidate for inclusion in this Pipeline, please submit a Preclinical Candidate Submission Form.

Pipeline updated 1 December 2025
Click on an individual candidate to see when it was last updated

Disclaimer
The TB Vaccine Pipeline (“Pipeline”) is provided for informational purposes. The information used in this Pipeline (“Information”) was reported by the sponsor/lead developer or found in the public domain associated with the specific candidate and should be considered “as is.” The Stop TB Partnership Working Group on New TB Vaccines does not guarantee or warrant the accuracy, completeness, or reliability of any of the Information displayed in this Pipeline. Use of any such Information, for whatever purpose, shall be at the user’s own risk and liability.