Posts by WGNV

Implications of subclinical tuberculosis for vaccine trial design and global effect. Churchyard GJ, Houben RMGJ, Fielding K, Fiore-Gartland AL, Esmail H, Grant AD, Rangaka MX, Behr M, Garcia-Basteiro AL, Wong EB, Hatherill M, Mave V, Dagnew AF, Schmidt AC, Hanekom WA, Cobelens F, White RG. Lancet Microbe. 2024 Jul 1. doi: 10.1016/S2666-5247(24)00127-7. Epub ahead of…

Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial. Dos Santos PCP, Messina NL, de Oliveira RD, da Silva PV, Puga MAM, Dalcolmo M, Dos Santos G, de Lacerda MVG, Jardim BA, de Almeida E Val FF, Curtis N, Andrews JR, Croda J. Lancet Infect Dis. 2024…

Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains. Painter H, Willcocks S, Zelmer A, Reljic R, Tanner R, Fletcher H. Tuberculosis (Edinb). 2024 May. doi: 10.1016/j.tube.2024.102494. Epub 2024 Feb 13.   Recognition of Mycobacterium tuberculosis by macrophage…

Perspectives on development and advancement of new tuberculosis vaccines. da Costa C, Benn CS, Nyirenda T, Mpabalwani E, Grewal HMS, Ahmed R, Kapata N, Nyasulu PS, Maeurer M, Hui DS, Goletti D, Zumla A. Int J Infect Dis. 2024 Apr. doi: 10.1016/j.ijid.2024.106987. Epub 2024 Feb 26.  Comparative transcriptomics reveals common and strain-specific responses of human…