BCGΔBCG1419c
This is a second-generation version of BCGΔBCG1419c, devoid of antibiotic markers. It is based on BCG Pasteur ATCC 35734.
Read MoreBCG (Travel vaccine)
The purpose of this trial (TIPI Trial), is to find out if a single dose of pre-travel vaccination with BCG can lessen tuberculosis (TB) infection by producing an immune response when given to adults traveling to countries with a high burden of TB. BCG (Tokyo 172), supplied by Japan BCG Lab, will be compared with…
Read MoreBCG (Revaccination)
The Gates MRI BCG ReVax trial is a Phase 2B trial conducted to inform policy. No label change or new indication is intended. The trial compares AJVaccines’ BCG (Danish 1331) to saline placebo for the prevention of sustained IGRA conversion (initial conversion and IGRA-positive 3 and 6 months post initial conversion), as a proxi for…
Read MoreMTBVAC
MTBVAC is an attenuated M. tuberculosis strain, by genetically engineering two independent unmarked stable deletion mutations in the virulence genes phoP and fadD26, based on clinical strain of the Euro-American lineage 4, the most widespread transmitted lineage between humans. MTBVAC includes RD1 absent in BCG, which contains 23% of the known human T-cell epitopes present…
Read MoreVPM1002
VPM1002 is a recombinant, urease C-deficient, listeriolysin expressing BCG vaccine strain and was generated in order to induce a broader immune response against mycobacterial antigens.
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