M72/AS01E
The M72/AS01E vaccine candidate consists of the M72 fusion protein and the proprietary GSK adjuvant system AS01E.
Read MoreMTBVAC (BBV169)
MTBVAC is an attenuated M. tuberculosis strain, by genetically engineering two independent unmarked stable deletion mutations in the virulence genes phoP and fadD26, based on clinical strain of the Euro-American lineage 4, the most widespread transmitted lineage between humans. MTBVAC includes RD1 absent in BCG, which contains 23% of the known human T-cell epitopes present…
Read MoreGamTBvac
GamTBvac is a recombinant vaccine containing three Mycobacterium tuberculosis (MTB) antigens: Ag85a and ESAT6-CFP10 fusion protein, fused with a dextran-binding domain (DBD) from Leuconostoc mesenteroides. These fusions are formulated with the adjuvant containing Dextran 500 kDa and DEAE-Dextran 500 kDa covered with CpG oligonucleotides.
Read MoreChAdOx1.85A+MVA85A
ChAdOx1.85A is a simian adenoviral vector expressing Antigen 85A. MVA85A is a modified vaccinia virus Ankara expressing Antigen 85A. The target route of administration for ChAdOx1.85A is aerosol, and intramuscular for MVA85A.
Read MoreDAR-901
DAR-901 is an inactivated whole cell vaccine derived from a non-tuberculous mycobacterium and represents a scalable manufacturing process for SRL172.
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