November 2020 Publications

Safety and Immunogenicity of the GamTBvac, the Recombinant Subunit Tuberculosis Vaccine Candidate: A Phase II, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study. Tkachuk AP, Bykonia EN, Popova LI, Kleymenov DA, Semashko MA, Chulanov VP, Fitilev SB, Maksimov SL, Smolyarchuk EA, Manuylov VA, Vasina DV, Gushchin VA, Gintsburg AL. Vaccines (Basel). 2020 Nov 3. doi: 10.3390/vaccines8040652.

Cell Envelope Proteomics of Mycobacteria. Hermann C, Karamchand L, Blackburn JM, Soares NC. J Proteome Res. 2020 Nov 3. doi: 10.1021/acs.jproteome.0c00650. Online ahead of print.

Early Vaccination With Bacille Calmette-Guerin-Denmark or BCG-Japan Versus BCG-Russia to Healthy Newborns in Guinea-Bissau: A Randomized Controlled Trial. Schaltz-Buchholzer F, Bjerregaard-Andersen M, Øland CB, Golding C, Stjernholm EB, Monteiro I, Aaby P, Benn CS. Clin Infect Dis. 2020 Nov 5;71(8):1883-1893. doi: 10.1093/cid/ciz1080.

2019: A Banner Year for Tuberculosis Research. Eisinger RW, Embry AC, Read SW, Fauci AS. J Infect Dis. 2020 Nov 9. doi: 10.1093/infdis/jiaa051.

Chemical synthesis and antigenic activity of a phosphatidylinositol mannoside epitope from Mycobacterium tuberculosis. Zhao SY, Li N, Luo WY, Zhang NN, Zhou RY, Li CY, Wang J. Chem Commun (Camb). 2020 Nov 12. doi: 10.1039/d0cc05573e.

Does the Bacillus Calmette-Guerin vaccine have different protective effects on various strains of tuberculosis? Kousha A, Farajnia S, Ansarin K, Khalili M, Shariat M, Sahebi L. Clin Exp Immunol. 2020 Nov 14. doi: 10.1111/cei.13549. Online ahead of print.

Airway Macrophages Mediate Mucosal Vaccine-Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection.D’Agostino MR, Lai R, Afkhami S, Khera A, Yao Y, Vaseghi-Shanjani M, Zganiacz A, Jeyanathan M, Xing Z. J Immunol. 2020 Nov 15. doi: 10.4049/jimmunol.2000532. Epub 2020 Sep 30

Identification of Autophagy-Inhibiting Factors of Mycobacterium tuberculosis by High-Throughput Loss-of-Function Screening. Strong EJ, Jurcic Smith KL, Saini NK, Ng TW, Porcelli SA, Lee S. Infect Immun. 2020 Nov 16. doi: 10.1128/IAI.00269-20.

Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions. Verma D, Chan ED, Ordway DJ. Vaccines (Basel). 2020 Nov 16. doi: 10.3390/vaccines8040688.

Proteomic characterization of a second-generation version of the BCGdeltaBCG1419c vaccine candidate by means of Electrospray-ionization quadrupole time-of-flight mass spectrometry. Velázquez-Fernández JB, Souza GHMF, Rodríguez-Campos J, Aceves-Sánchez MJ, Bravo-Madrigal J, Vallejo-Cardona AA, Flores-Valdez MA. Pathog Dis. 2020 Nov 17. doi: 10.1093/femspd/ftaa070. Online ahead of print.

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils. Moorlag SJCFM, Rodriguez-Rosales YA, Gillard J, Fanucchi S, Theunissen K, Novakovic B, de Bont CM, Negishi Y, Fok ET, Kalafati L, Verginis P, Mourits VP, Koeken VACM, de Bree LCJ, Pruijn GJM, Fenwick C, van Crevel R, Joosten LAB, Joosten I, Koenen H, Mhlanga MM, Diavatopoulos DA, Chavakis T, Netea MG. Cell Rep. 2020 Nov 17. doi: 10.1016/j.celrep.2020.108387.

Is mapping the BCG vaccine-induced immune responses the key to improving the efficacy against tuberculosis? Kuan R, Muskat K, Peters B, Lindestam Arlehamn CS. J Intern Med. 2020 Nov 19. doi: 10.1111/joim.13191. Online ahead of print.

BCG Vaccination of Infants Confers Mycobacterium tuberculosis Strain-Specific Immune Responses by Leukocytes. Subbian S, Singh P, Kolloli A, Nemes E, Scriba T, Hanekom WA, Kaplan G. ACS Infect Dis. 2020 Nov 23. doi: 10.1021/acsinfecdis.0c00696. Online ahead of print.

Genetic Diversity in Mycobacterium tuberculosis Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease. Peters JS, Ismail N, Dippenaar A, Ma S, Sherman DR, Warren RM, Kana BD. Annu Rev Genet. 2020 Nov 23. doi: 10.1146/annurev-genet-022820-085940. Epub 2020 Sep 14.

Cost-Effectiveness Analysis of BCG Vaccination against Tuberculosis in Indonesia: A Model-Based Study. Machlaurin A, Dolk FCK, Setiawan D, van der Werf TS, Postma MJ. Vaccines (Basel). 2020 Nov 26;8(4):707. doi: 10.3390/vaccines8040707.

Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery. Abdelwahab WM, Riffey A, Buhl C, Johnson C, Ryter K, Evans JT, Burkhart DJ. Int J Pharm. 2020 Nov 26. doi: 10.1016/j.ijpharm.2020.120119. Online ahead of print.

Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages.  Kadir NA, Acosta A, Sarmiento ME, Norazmi MN. Pathogens. 2020 Nov 29. doi: 10.3390/pathogens9121000.