Posts by WGNV

Safety, reactogenicity, and immunogenicity of MTBVAC in infants: a phase 2a randomised, double-blind, dose-defining trial in a TB endemic setting. Tameris M, Rozot V, Imbratta C, Geldenhuys H, Mendelsohn SC, Kany Luabeya AK, Shenje J, Tredoux N, Fisher M, Mulenga H, Bilek N, Young C, Veldsman A, Botes N, Thole J, Fritzell B, Mukherjee R,…

Microneedle-mediated intradermal delivery of Bacille Calmette-Guérin (BCG) vaccines for single-dose tuberculosis vaccination. Lee S, Kim T, Seong KY, Yim SG, Lee WK, Kim S, Lee KO, Yang SY, Ryoo S. Tuberculosis (Edinb). 2025 Mar;151:102608. doi: 10.1016/j.tube.2025.102608. Epub 2025 Jan 16.   An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4+ T cell…

Tuberculosis and T cells: Impact of T cell diversity in tuberculosis infection. Vats D, Rani G, Arora A, Sharma V, Rathore I, Mubeen SA, Singh A. Tuberculosis (Edinb). 2024 Dec;149:102567. doi: 10.1016/j.tube.2024.102567. Epub 2024 Sep 18.   A multistage Sendai virus vaccine incorporating latency-associated antigens induces protection against acute and latent tuberculosis. Hu Z, Xia…

Bioinformatics Analysis and Immunogenicity Assessment of the Novel Multi-Stage DNA Vaccine W541 Against Mycobacterium Tuberculosis. Yang Y, Xue Y, Wang X, Wang L, Wang J, Zhang J, Liu Y, Liang Y, Wu X. Immun Inflamm Dis. 2024 Nov;12(11):e70074. doi: 10.1002/iid3.70074.  Multilevel Proteomics Reveals Epigenetic Signatures in BCG-Mediated Macrophage Activation. Schaefer Z, Iradukunda J, Lumngwena EN,…