Posts by WGNV

Implications of subclinical tuberculosis for vaccine trial design and global effect Churchyard GJ, Houben RMGJ, Fielding K, Fiore-Gartland AL, Esmail H, Grant AD, Rangaka MX, Behr M, Garcia-Basteiro AL, Wong EB, Hatherill M, Mave V, Dagnew AF, Schmidt AC, Hanekom WA, Cobelens F, White RG. Lancet Microbe. 2024 Oct;5(10):100895. doi: 10.1016/S2666-5247(24)00127-7. Epub 2024 Jul 1. …

Immunoproteomic discovery of Mycobacterium bovis antigens, including the surface lipoprotein Mpt83 as a T cell antigen useful for vaccine development. Karunakaran KP, Yu H, Jiang X, Chan QWT, Sigola L, Millis LA, Chen J, Tang P, Foster LJ, Brunham RC. Vaccine. 2024 Sep 2;42(24):126266. doi: 10.1016/j.vaccine.2024.126266. Epub ahead of print.   Antibodies as key mediators…

Implications of subclinical tuberculosis for vaccine trial design and global effect. Churchyard GJ, Houben RMGJ, Fielding K, Fiore-Gartland AL, Esmail H, Grant AD, Rangaka MX, Behr M, Garcia-Basteiro AL, Wong EB, Hatherill M, Mave V, Dagnew AF, Schmidt AC, Hanekom WA, Cobelens F, White RG. Lancet Microbe. 2024 Jul 1. doi: 10.1016/S2666-5247(24)00127-7. Epub ahead of…

Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial. Dos Santos PCP, Messina NL, de Oliveira RD, da Silva PV, Puga MAM, Dalcolmo M, Dos Santos G, de Lacerda MVG, Jardim BA, de Almeida E Val FF, Curtis N, Andrews JR, Croda J. Lancet Infect Dis. 2024…

Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains. Painter H, Willcocks S, Zelmer A, Reljic R, Tanner R, Fletcher H. Tuberculosis (Edinb). 2024 May. doi: 10.1016/j.tube.2024.102494. Epub 2024 Feb 13.   Recognition of Mycobacterium tuberculosis by macrophage…