December 2021 Publications
- BCG vaccination strategies against tuberculosis: updates and perspectives. Qu M, Zhou X, Li H. Hum Vaccin Immunother. 2021 Dec 2. doi: 10.1080/21645515.2021.2007711. Online ahead of print.
- Recombinant BCGs for tuberculosis and bladder cancer. Singh AK, Srikrishna G, Bivalacqua TJ, Bishai WR. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.09.040. Epub 2021 Sep 27.
- Immunological Assessment of Chitosan or Trimethyl Chitosan-Coated PLGA Nanospheres Containing Fusion Antigen as the Novel Vaccine Candidates Against Tuberculosis. Zare S, Kabiri M, Amini Y, Najafi A, Mohammadpour F, Ayati SH, Nikpoor AR, Tafaghodi M. AAPS PharmSciTech. 2021 Dec 10. doi: 10.1208/s12249-021-02146-z.
- Trained immunity contributes to the prevention of Mycobacterium tuberculosis infection, a novel role of autophagy. Zhou J, Lv J, Carlson C, Liu H, Wang H, Xu T, Wu F, Song C, Wang X, Wang T,Qian Z. Emerg Microbes Infect.2021 Dec. doi: 10.1080/22221751.2021.1899771.
- Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females. Nieuwenhuizen NE, Zyla J, Zedler U, Bandermann S, Abu Abed U, Brinkmann V, Kaufmann SHE. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.09.039. Epub 2021 Sep 30.
- MTBVAC, a live TB vaccine poised to initiate efficacy trials 100 years after BCG. Martín C, Marinova D, Aguiló N, Gonzalo-Asensio J. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.06.049. Epub 2021 Jul 6.
- Where are the RNA vaccines for TB? Fan XY, Lowrie DB. Emerg Microbes Infect. 2021 Dec. doi: 10.1080/22221751.2021.1935328.
- A BCG success story: From prevention of tuberculosis to optimal bladder cancer treatment. Lamm DL, Morales A. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.08.026. Epub 2021 Aug 18.
- Meeting report: Virtual Global Forum on Tuberculosis Vaccines, 20-22 April 2021. Suliman S, Pelzer PT, Shaku M, Rozot V, Mendelsohn SC. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.08.094. Epub 2021 Sep 15.
- Inclusion of Additional Unintended Consequences in Economic Evaluation: A Systematic Review of Immunization and Tuberculosis Cost-Effectiveness Analyses. Nymark LS, Miller A, Vassall A.Pharmacoecon Open. 2021 Dec. doi: 10.1007/s41669-021-00269-4. Epub 2021 May 4.
- The role of antibodies in Bacille Calmette Guérin-mediated immune responses and protection against tuberculosis in humans: A systematic review. Bright MR, Curtis N, Messina NL. Tuberculosis. 2021 Dec. doi: 10.1016/j.tube.2020.101947. Epub 2020 Jun 9.
- ESX-5-targeted export of ESAT-6 in BCG combines enhanced immunogenicity & efficacy against murine tuberculosis with low virulence and reduced persistence. Heijmenberg I, Husain A, Sathkumara HD, Muruganandah V, Seifert J, Miranda-Hernandez S, Kashyap RS, Field MA, Krishnamoorthy G, Kupz A. Vaccine. 2021 Dec 8. doi: 10.1016/j.vaccine.2021.08.030. Epub 2021 Aug 19.
- Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques. Irvine EB, O’Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, Alter G. Nat Immunol. 2021 Dec. doi: 10.1038/s41590-021-01066-1. Epub 2021 Nov 22
- The effect of new Mycobacterium tuberculosis infection on the sensitivity of prognostic TB signatures. Sumner T, Fiore-Gartland A, Hatherill M, Houben RMGJ, Scriba TJ, White RG. Int J Tuberc Lung Dis. 2021 Dec 1. doi: 10.5588/ijtld.21.0323.
- Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease. Burel JG, Singhania A, Dubelko P, Muller J, Tanner R, Parizotto E, Dedicoat
- M, Fletcher TE, Dunbar J, Cunningham AF, Lindestam Arlehamn CS, Catanzaro DG, Catanzaro A, Rodwell T, McShane H, O’Shea MK, Peters B. Tuberculosis. 2021 Dec. doi: 10.1016/j.tube.2021.102127. Epub 2021 Sep 14.
- Quantitative proteomics reveals that dormancy-related proteins mediate the attenuation in mycobacterium strains. Wang H, Wan L, Shi J, Zhang T, Zhu H, Jiang S, Meng S, Wu S, Sun J, Chang L, Zhang L, Wan K, Yang J, Zhao X, Liu H, Zhang Y, Dai E, Xu P. Virulence. 2021 Dec. doi: 10.1080/21505594.2021.1965703.
- The impact of a change in infant BCG vaccination policy on adolescent TB incidence rates: A South African population-level cohort study. Fack C, Wood R, Hatherill M, Cobelens F, Hermans S. Vaccine. 2021 Dec 3. doi: 10.1016/j.vaccine.2021.11.043. Online ahead of print.
- CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature. Singhania A, Dubelko P, Kuan R, Chronister WD, Muskat K, Das J, Phillips EJ, Mallal SA, Seumois G, Vijayanand P, Sette A, Lerm M, Peters B, Lindestam Arlehamn C. EBioMedicine. 2021 Dec 10. doi: 10.1016/j.ebiom.2021.103746. Online ahead of print.
- Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis. Mulenga H, Musvosvi M, Mendelsohn SC, Penn-Nicholson A, Kimbung Mbandi S, Fiore-Gartland A, Tameris M, Mabwe S, Africa H, Bilek N, Kafaar F, Khader SA, Carstens B, Hadley K, Hikuam C, Erasmus M, Jaxa L, Raphela R, Nombida O, Kaskar M, Nicol MP, Mbhele S, Van Heerden J, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Walzl G, Naidoo K, Churchyard G, Hatherill M, Scriba TJ; CORTIS Study Team. Am J Respir Crit Care Med. 2021 Dec 15. doi: 10.1164/rccm.202103-0548OC.
- A simple assay to quantify mycobacterial lipid antigen-specific T cell receptors in human tissues and blood. Zhou AX, Scriba TJ, Day CL, Hagge DA, Seshadri C. PLoS Negl Trop Dis. 2021 Dec 16. doi: 10.1371/journal.pntd.0010018. Online ahead of print.
- Mucosal Vaccination with Cyclic Dinucleotide Adjuvants Induces Effective T Cell Homing and IL-17-Dependent Protection against Mycobacterium tuberculosis Infection. Jong RM, Van Dis E, Berry SB, Nguyenla X, Baltodano A, Pastenkos G, Xu C, Fox D, Yosef N, McWhirter SM, Stanley SA. J Immunol. 2021 Dec 29. doi: 10.4049/jimmunol.2100029. Online ahead of print.