July 2021 Publications
- Neonatal Bacille Calmette-Guérin vaccination and tuberculin skin test reactions at 2-and 6-months: Effects on mortality up to 1 year of age. Schaltz-Buchholzer F, Roth A, de Bree LCJ, Biering-Sørensen, S, Timmermann CAG, Monteiro I, Aaby P, Benn CS. Vaccine. 2021 July 2. doi: 10.1016/j.vaccine.2021.06.077.
- The Effect of BCG on Mortality Beyond Infancy: 30-Year Follow-Up of a Double-Blind Randomised Placebo-Controlled Trial of BCG Re-Vaccination in Malawi. Glynn JR, Dube A, Fielding K, Crampin AC, Kanjala C, Fine P. Lancet preprints. 2021 July 5. doi: 10.1016/S1473-3099(20)30994-4.
- Thirty years of recombinant BCG: new trends for a centenary vaccine. Marques-Neto LM, Piwowarska Z, Kanno AI, Moraes L, Trentini MM, Rodriguez D, Silva J, Leite L. Thirty years of recombinant BCG: new trends for a centenary vaccine. Expert Rev Vaccines. 2021 Jul 5. doi: 10.1080/14760584.2021.1951243. Epub ahead of print. PMID: 34224293.
- An immunoinformatics approach to design a multi-epitope vaccine against Mycobacterium tuberculosis exploiting secreted exosome proteins. Sharma R, Rajput VS, Jamal S, Grover A, Grover S. Sci Rep. 2021 July 5. doi: 10.1038/s41598-021-93266-w.
- MTBVAC, a live TB vaccine poised to initiate efficacy trials 100 years after BCG. Martín C, Marinova, D, Aguiló N, Gonzalo-Asensio J. Vaccine. 2021 July 5. doi: 10.1016/j.vaccine.2021.06.049.
- Cumulative Signaling Through NOD-2 and TLR-4 Eliminates the Mycobacterium Tuberculosis Concealed Inside the Mesenchymal Stem Cells. Aqdas M, Singh S, Amir M, Maurya SK, Pahari S, Agrewala JN. Front Cell Infect Microbiol. 2021 July 7. doi: 10.3389/fcimb.2021.669168.
- T helper type 1 biased immune responses by PPE17 loaded core-shell alginate-chitosan nanoparticles after subcutaneous and intranasal administration. Najafi A, Ghazvini K, Sankian M, Gholami L, Amini Y, Zare S, Khademi F, Tafaghodi M. Life Sci. 2021 July 9. doi: 10.1016/j.lfs.2021.119806.
- Evaluation of the stability of a spray-dried tuberculosis vaccine candidate designed for dry powder respiratory delivery. Gomez M, McCollum J, Wang H, Bachchhav S, Tetreau I, Gerhardt A, Press C, Kramer RM, Fox CB, Vehring R. Vaccine. 2021 July 10. doi: 10.1016/j.vaccine.2021.07.002.
- Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4+ T Cell Activation and Mycobacterium tuberculosis Control. Das S, Marin ND, Esaulova E, Ahmed M, Swain A, Rosa BA, Mitreva M, Rangel-Moreno J, Netea MG, Barreiro LB, Divangahi M, Artyomov MN, Kaushal D, Khader SA. mBio. 2021 Jul 13. doi: 10.1128/mBio.01468-21.
- Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation In Vitro. Angelidou A, Diray-Arce J, Conti MG, Netea MG, Blok BA, Liu M, Sanchez-Schmitz G, Ozonoff A, van Haren SD, Levy O. Front Immunol. 2021 Jul 13. doi: 10.3389/fimmu.2021.674334.
- Mycobacterium tuberculosis RpfE-Induced Prostaglandin E2 in Dendritic Cells Induces Th1/Th17 Cell Differentiation. Park HS, Choi S, Back YW, Lee KI, Choi HG, Kim HJ. Int J of Mol Sci. 2021 July 14. doi: 10.3390/ijms22147535.
- BCG vaccination induces enhanced frequencies of dendritic cells and altered plasma levels of type I and type III interferons in elderly individuals. Kumar NP, Padmapriyadarsini C, Rajamanickam A, Bhavani PK, Nancy A, Jayadeepa B, Selvaraj N, Ashokan D, Renji RM, Venkataramani V, Tripathy S, Babu S. Int J Infect Dis. 2021 July 22. doi: 10.1016/j.ijid.2021.07.041.
- BCG therapy is associated with long-term, durable induction of Treg signature genes by epigenetic modulation. Keefe RC, Takahashi H, Tran L, Nelson K, Ng N, Kühtreiber WM, Faustman DL. Sci Rep. 2021 July 22. doi: 10.1038/s41598-021-94529-2.
- Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung. Pisu D, Huang L, Narang V, Theriault M, Lê-Bury G, Lee B, Lakudzala AE, Mzinza DT, Mhango DV, Mitini-Nkhoma SC, Jambo KC, Singhal A, Mwandumba HC, Russell DG. J Exp Med. 2021 Sep 6. doi: 10.1084/jem.20210615. Epub 2021 Jul 22.
- Immunoinformatics analysis of antigenic epitopes and designing of a multi-epitope peptide vaccine from putative nitro-reductases of M. tuberculosis DosR. Shiraz M, Lata S, Kumar P, Shankar UN, Akif M. Infect Genet Evol. 2021 Jul 28. doi: 10.1016/j.meegid.2021.105017.
- Protective immunity against tuberculosis in a free-living badger population vaccinated orally with Mycobacterium bovis Bacille Calmette Guérin (BCG). Gormley E, Ní Bhuachalla D, Fitzsimons T, O’Keeffe J, McGrath G, Madden JM, Fogarty N, Kenny K, Messam LLM, Murphy D, Corner LAL. Transbound Emerg Dis. 2021 Jul 31. doi: 10.1111/tbed.14254.
- Engineering a new vaccine platform for heterologous antigen delivery in live-attenuated Mycobacterium tuberculosis. Broset E, Seral JC, Arnal C, Uranga S, Kanno AI, Leite LC, Martín C, Gonzalo-Asensio J. Comput Struct Biotechnol J. 2021 Jul 30. doi: 10.1016/j.csbj.2021.07.035.