September 2024 Publications
- Immunoproteomic discovery of Mycobacterium bovis antigens, including the surface lipoprotein Mpt83 as a T cell antigen useful for vaccine development. Karunakaran KP, Yu H, Jiang X, Chan QWT, Sigola L, Millis LA, Chen J, Tang P, Foster LJ, Brunham RC. Vaccine. 2024 Sep 2;42(24):126266. doi: 10.1016/j.vaccine.2024.126266. Epub ahead of print.
- Antibodies as key mediators of protection against Mycobacterium tuberculosis. Wang Q, Nag D, Baldwin SL, Coler RN, McNamara RP. Front Immunol. 2024 Sep 2;15:1430955. doi: 10.3389/fimmu.2024.1430955.
- Advancing Human Vaccine Development Using Humanized Mouse Models. Han R, Su L, Cheng L. Vaccines (Basel). 2024 Sep 4;12(9):1012. doi: 10.3390/vaccines12091012.
- A second-generation recombinant BCG strain combines protection against murine tuberculosis with an enhanced safety profile in immunocompromised hosts . Valencia-Hernandez AM, Zhao G, Miranda-Hernandez S, Segura-Cerda CA, Pedroza-Roldan C, Seifert J, Aceves-Sanchez MJ, Burciaga-Flores M, Gutierrez-Ortega A, Del Pozo-Ramos L, Flores-Valdez MA, Kupz A. Vaccine. 2024 Sep 5;42(24):126291. doi: 10.1016/j.vaccine.2024.126291. Epub ahead of print.
- Development of innovative multi-epitope mRNA vaccine against central nervous system tuberculosis using in silico approaches. Shi H, Zhu Y, Shang K, Tian T, Yin Z, Shi J, He Y, Ding J, Wang Q, Zhang F. PLoS One. 2024 Sep 6;19(9):e0307877. doi: 10.1371/journal.pone.0307877.
- Intranasal Immunization with a Recombinant Adenovirus Encoding Multi-Stage Antigens of Mycobacterium tuberculosis Preferentially Elicited CD8+ T Cell Immunity and Conferred a Superior Protection in the Lungs of Mice than Bacillus Calmette-Guerin . Wang L, Kang J, Jiang H. 2024 Sep 6;12(9):1022. doi: 10.3390/vaccines12091022.
- In silico design of Mycobacterium tuberculosis multi-epitope adhesin protein vaccines. Pillay K, Chiliza TE, Senzani S, Pillay B, Pillay M. Heliyon. 2024 Sep 7;10(18):e37536. doi: 10.1016/j.heliyon.2024.e37536.
- Early transcriptomic response of innate immune cells to subcutaneous BCG vaccination of mice. Kondratyeva L, Kuzmich A, Linge I, Pleshkan V, Rakitina O, Kondratieva S, Snezhkov E, Sass A, Alekseenko I. BMC Res Notes. 2024 Sep 9;17(1):253. doi: 10.1186/s13104-024-06901-w.
- The role of inflammasomes as central inflammatory hubs in Mycobacterium tuberculosis infection. Theobald SJ, Müller TA, Lange D, Keck K, Rybniker J. Front Immunol. 2024 Sep 11;15:1436676. doi: 10.3389/fimmu.2024.1436676.
- An intranasal nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis. Sefat KMSR, Kumar M, Kehl S, Kulkarni R, Leekha A, Paniagua MM, Ackart DF, Jones N, Spencer C, Podell BK, Ouellet H, Varadarajan N. Vaccine. 2024 Sep 17;42(22):125909. doi: 10.1016/j.vaccine.2024.04.055. Epub 2024 May 3.
- Intranasal vaccination with engineered BCG expressing CCL2 induces a stronger immune barrier against Mycobacterium tuberculosis than BCG. Guo S, Ouyang J, Hu Z, Cao T, Huang C, Mou J, Gu X, Liu J. Mol Ther. 2024 Sep 17:S1525-0016(24)00609-9. doi: 10.1016/j.ymthe.2024.09.021. Epub ahead of print.
- Tuberculosis and T cells: Impact of T cell diversity in tuberculosis infection. Vats D, Rani G, Arora A, Sharma V, Rathore I, Mubeen SA, Singh A. Tuberculosis (Edinb). 2024 Sep 18;149:102567. doi: 10.1016/j.tube.2024.102567. Epub ahead of print.
- Enhanced Antimicrobial Peptide Response Following Bacillus Calmette-Guerin Vaccination in Elderly Individuals. Pandiarajan AN, Kumar NP, Rajamanickam A, Bhavani PK, Jeyadeepa B, Selvaraj N, Asokan D, Tripathy S, Padmapriyadarsini C, Babu S. Vaccines (Basel). 2024 Sep 18;12(9):1065. doi: 10.3390/vaccines12091065.
- Mycobacterium tuberculosis VII secretion system effector molecule Rv2347c blocks the maturation of phagosomes and activates the STING/TBK1 signaling pathway to inhibit cell autophagy Jiang Z, Zhen J, Abulikena Y, Gao C, Huang L, Huang T, Xie J. Microbiol Spectr. 2024 Sep 23:e0118824. doi: 10.1128/spectrum.01188-24. Epub ahead of print.
- Intravenous Bacillus Calmette-Guérin (BCG) Induces a More Potent Airway and Lung Immune Response than Intradermal BCG in Simian Immunodeficiency Virus-infected Macaques . Jauro S, Larson EC, Gleim JL, Wahlberg BM, Rodgers MA, Chehab JC, Lopez-Velazques AE, Ameel CL, Tomko JA, Sakal JL, DeMarco T, Borish HJ, Maiello P, Potter EL, Roederer M, Ling Lin P, Flynn JL, Scanga CA. J Immunol. 2024 Sep 23:ji2400417. doi: 10.4049/jimmunol.2400417. Epub ahead of print.
- Therapy modulates the response to T cell epitopes over the spectrum of tuberculosis infection . Petrone L, Peruzzu D, Altera AMG, Salmi A, Vanini V, Cuzzi G, Coppola A, Mellini V, Gualano G, Palmieri F, Panda S, Peters B, Sette A, Arlehamn CL, Goletti D. J Infect. 2024 Sep 27:106295. doi: 10.1016/j.jinf.2024.106295. Epub ahead of print.