May 2024 Publications
- Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains. Painter H, Willcocks S, Zelmer A, Reljic R, Tanner R, Fletcher H. Tuberculosis (Edinb). 2024 May. doi: 10.1016/j.tube.2024.102494. Epub 2024 Feb 13.
- Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy. Wei L, Liu L, Meng Z, Qi K, Gao X, Feng J, Luo J. Inflamm Res. 2024 May. doi: 10.1007/s00011-024-01864-x. Epub 2024 Apr 2.
- Rapamycin improves the long-term T-cell memory and protective efficacy of tuberculosis subunit vaccine. Niu H, Bai C, Zhu B, Zhang Y. Microb Pathog. 2024 May doi: 10.1016/j.micpath.2024.106631. Epub 2024 Mar 26.
- An intranasal nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis. Sefat KMSR, Kumar M, Kehl S, Kulkarni R, Leekha A, Paniagua MM, Ackart DF, Jones N, Spencer C, Podell BK, Ouellet H, Varadarajan N. Vaccine. 2024 May 3. doi: 10.1016/j.vaccine.2024.04.055. Epub ahead of print.
- Effects of non-tuberculous mycobacteria on BCG vaccine efficacy: A narrative review. Ghasemi F, Kardan-Yamchi J, Heidary M, Karami-Zarandi M, Akrami S, Maleki A, Khoshnood S, Kazemian H. J Clin Tuberc Other Mycobact Dis. 2024 May 4. doi: 10.1016/j.jctube.2024.100451.
- Review of the current TB human infection studies for use in accelerating TB vaccine development: A meeting report. Balasingam S, Dheda K, Fortune S, Gordon SB, Hoft D, Kublin JG, Loynachan CN, McShane H, Morton B, Nambiar S, Sharma NR, Robertson B, Schrager LK, Weller CL. J Infect Dis. 2024 May 6. doi: 10.1093/infdis/jiae238. Epub ahead of print.
- Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction. Mubarak AS, Ameen ZS, Hassan AS, Ozsahin DU. Sci Rep. 2024 May 6. doi: 10.1038/s41598-024-59291-1.
- Susceptibility testing of the live attenuated tuberculosis vaccine BCG and the vaccine candidate MTBVAC to currently WHO-recommended anti-tuberculosis drugs by the European committee on antimicrobial susceptibility testing (EUCAST) method. Rabodoarivelo MS, Gómez AB, Picó Marco A, Martín C, Ramón-García S. Clin Microbiol Infect. 2024 May 7 doi: 10.1016/j.cmi.2024.04.017. Epub ahead of print.
- MR1-restricted T cell clonotypes are associated with “resistance” to Mycobacterium tuberculosis infection. Cross DL, Layton ED, Yu KK, Smith MT, Aguilar MS, Li S, Wilcox EC, Chapuis AG, Mayanja-Kizza H, Stein CM, Boom WH, Hawn TR, Bradley P, Newell EW, Seshadri C. JCI Insight. 2024 May 8. doi: 10.1172/jci.insight.166505.
- Extracellular vesicles in mycobacteria: new findings in biogenesis, host-pathogen interactions, and diagnostics. Salgueiro VC, Passemar C, Vázquez-Iniesta L, Lerma L, Floto A, Prados-Rosales R. mBio. 2024 May 8. doi: 10.1128/mbio.02552-23. Epub 2024 Apr 3.
- Bergenin potentiates BCG efficacy by enriching mycobacteria-specific adaptive memory responses via the Akt-Foxo-Stat4 axis. Mukhopadhyay S, Pahuja I, Okieh AA, Pandey D, Yadav V, Bhaskar A, Dwivedi VP. Tuberculosis (Edinb). 2024 May 8. doi: 10.1016/j.tube.2024.102517. Epub ahead of print.
- Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates. Peralta Alvarez MP, Jones H, Redondo Azema H, Davis C, White AD, Sarfas C, Dennis M, Li S, Wright D, Puentes E, Kimuda S, Belij-Rammerstorfer S, Aguilo N, Martin C, Sharpe S, McShane H, Tanner R. Front Immunol. 2024 May 10. doi: 10.3389/fimmu.2024.1387454.
- Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria. Veerapandian R, Gadad SS, Jagannath C, Dhandayuthapani S. Vaccines (Basel). 2024 May 12. doi: 10.3390/vaccines12050530.
- Analysis of the components of Mycobacterium tuberculosis heat-resistant antigen (Mtb-HAg) and its regulation of γδ T-cell function. Wei J, Guo F, Song Y, Feng T, Wang Y, Xu K, Song J, Kaysar E, Abdukayyum R, Lin F, Li K, Li B, Qian Z, Wang X, Wang H, Xu T. Cell Mol Biol Lett. 2024 May 13. doi: 10.1186/s11658-024-00585-7.
- Phase 1 Open-Label Dose Escalation Trial for the Development of a Human Bacillus Calmette-Guérin Challenge Model for Assessment of Tuberculosis Immunity In Vivo. Blazevic A, Edwards RL, Xia M, Eickhoff CS, Hamzabegovic F, Meza KA, Ning H, Tennant J, Mosby KJ, Ritchie JC, Girmay T, Lai L, McCullough M, Beck A, Kelley C, Edupuganti S, Kabbani S, Buchanan W, Makhene MK, Voronca D, Cherikh S, Goll JB, Rouphael NG, Mulligan MJ, Hoft DF. J Infect Dis. 2024 May 15. doi: 10.1093/infdis/jiad441.
- The whole genome sequence of Polish vaccine strain Mycobacterium bovis BCG Moreau. Krysztopa-Grzybowska K, Lach J, Polak M, Strapagiel D, Dziadek J, Olszewski M, Zasada AA, Darlińska A, Lutyńska A, Augustynowicz-Kopeć E. Microbiol Spectr. 2024 May 17. doi: 10.1128/spectrum.04259-23. Epub ahead of print.
- Bacteriophage T4 as a Protein-Based, Adjuvant- and Needle-Free, Mucosal Pandemic Vaccine Design Platform. Zhu J, Tao P, Chopra AK, Rao VB. Annu Rev Virol. 2024 May 20. doi: 10.1146/annurev-virology-111821-111145. Epub ahead of print.
- Current landscape of exosomes in tuberculosis development, diagnosis, and treatment applications. Sun X, Li W, Zhao L, Fan K, Qin F, Shi L, Gao F, Zheng C. Front Immunol. 2024 May 23. doi: 10.3389/fimmu.2024.1401867.
- Comparison of the transcriptome, lipidome, and c-di-GMP production between BCGΔBCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages. Flores-Valdez MA, Peterson EJR, Aceves-Sánchez MJ, Baliga NS, Morita YS, Sparks IL, Saini DK, Yadav R, Lang R, Mata-Espinosa D, León-Contreras JC, Hernández-Pando R. Sci Rep. 2024 May 24. doi: 10.1038/s41598-024-61815-8.
- Mycobacterium tuberculosis antigen 85B modifies BCG-induced antituberculosis immunity and favors pathogen survival. Piccaro G, Aquino G, Gigantino V, Tirelli V, Sanchez M, Iorio E, Matarese G, Cassone A, Palma C. J Leukoc Biol. 2024 May 29. doi: 10.1093/jleuko/qiae014.
- Immune Response to the Recombinant Apa Protein from Mycobacterium tuberculosis Expressed in Streptomyces lividans After Intranasal Administration in Mice. Induction of Protective Response to Tubercle Bacillus Aerosols Exposure. Martínez-Sotelo JA, Vallecillo AJ, Parada C, Segura E, Campuzano J, Silva-Miranda M, Servín-González L, Espitia C. Curr Microbiol. 2024 May 30. doi: 10.1007/s00284-024-03697-7.