February 2022 Publications
- Cost-effectiveness of routine adolescent vaccination with an M72/AS01E -like tuberculosis vaccine in South Africa and India. Harris RC, Quaife M, Weerasuriya C, Gomez GB, Sumner T, Bozzani F, White RG. Nat Commun. 2022 Feb 1. doi: 10.1038/s41467-022-28234-7.
- Deletion of BCG_2432c from the Bacillus Calmette-Guérin vaccine enhances autophagy-mediated immunity against tuberculosis. Wu Y, Tian M, Zhang Y, Peng H, Lei Q, Yuan X, Liu S, Xiong Y, Lin X, Jo-Lewis BN, Yao Z, Fu H, Fan X. Allergy. 2022 Feb. doi: 10.1111/all.15158. Epub 2021 Nov 7.
- Building the concept for WHO Evidence Considerations for Vaccine Policy (ECVP): Tuberculosis vaccines intended for adults and adolescents as a test case. Kochhar S, Barreira D, Beattie P, Cavaleri M, Cravioto A, Frick MW, Ginsberg. AM, Hudson I, Kaslow DC, Kurtz S, Lienhardt C, Madhi SA, Morgan C, Momeni Y, Patel D, Rees H, Rogalski-Salter T, Schmidt A, Semete-Makokotlela B, Voss G, White RG, Zignol M, Giersing B. Vaccine. 2022 Feb 11. doi: 10.1016/j.vaccine.2021.10.062. Online ahead of print.
- Protease-Based Subunit Vaccine in Mice Boosts BCG Protection against Mycobacterium tuberculosis. Junqueira-Kipnis AP, de Castro Souza C, de Oliveira Carvalho AC, de Oliveira FM, Almeida VP, de Paula AR, Celes MR, Kipnis A. Vaccines (Basel). 2022 Feb 16. doi: 10.3390/vaccines10020306.
- BCG-mediated protection against M. tuberculosis is sustained post-malaria infection independent of parasite virulence. Tangie E, Walters A, Hsu NJ, Fisher M, Magez S, Jacobs M, Keeton R. Immunology. 2022 Feb. doi: 10.1111/imm.13431. Epub 2021 Dec 6.
- Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans. Jeyanathan M, Fritz DK, Afkhami S, Aguirre E, Howie KJ, Zganiacz A, Dvorkin-Gheva A, Thompson MR, Silver RF, Cusack RP, Lichty BD, O’Byrne PM, Kolb M, Medina MFC, Dolovich MB, Satia I, Gauvreau GM, Xing Z, Smaill F. JCI Insight. 2022 Feb 8. doi: 10.1172/jci.insight.155655.
- The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk. Mulenga H, Fiore-Gartland A, Mendelsohn SC, Penn-Nicholson A, Mbandi SK, Borate B, Musvosvi M, Tameris M, Walzl G, Naidoo K, Churchyard G, Scriba TJ, Hatherill M; CORTIS Yu W, Shen L, Qi Q, Hu T. Eur J Pharm Biopharm. 2022 Feb 17. doi: 10.1016/j.ejpb.2022.02.011. Online ahead of print.
- Augmentation of the Riboflavin-Biosynthetic Pathway Enhances Mucosa-Associated Invariant T (MAIT) Cell Activation and Diminishes Mycobacterium tuberculosis Virulence. Dey RJ, Dey B, Harriff M, Canfield ET, Lewinsohn DM, Bishai WR. mBio. 2022 Feb 15. doi: 10.1128/mbio.03865-21. Epub ahead of print.
- IL-10 Receptor Blockade Delivered Simultaneously with Bacillus Calmette-Guérin Vaccination Sustains Long-Term Protection against Mycobacterium tuberculosis Infection in Mice. Dwivedi V, Gautam S, Headley CA, Piergallini T, Torrelles JB, Turner J. J Immunol. 2022 Feb 18. doi: 10.4049/jimmunol.2100900. Online ahead of print.
- Immunogenic profiling of Mycobacterium tuberculosis DosR protein Rv0569 reveals its ability to switch on Th1 based immunity. Kanaparthi KJ, Afroz S, Minhas G, Moitra A, Khan RA, Medikonda J, Naz S, Cholleti SN, Banerjee S, Khan N. Immunol Lett. 2022 Feb. doi: 10.1016/j.imlet.2022.01.001. Epub 2022 Jan 7.
- Identification of MicroRNAs as Potential Blood-Based Biomarkers for Diagnosis and Therapeutic Monitoring of Active Tuberculosis. Kim J, Park H, Park SB, Lee EJ, Je MA, Ahn E, Sim B, Lee J, Jin H, Lee KE, Cho SN, Kang YA, Lee H, Kim S, Kim J. Diagnostics (Basel). 2022 Feb 1. doi: 10.3390/diagnostics12020369.
- Human lymph node immune dynamics as driver of vaccine efficacy: an understudied aspect of immune responses. Moysi E, Paris RM, Le Grand R, Koup RA, Petrovas C. Expert Rev Vaccines. 2022 Feb 23. doi: 10.1080/14760584.2022.2045198. Online ahead of print.
- REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk. Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. J Immunol. 2022 Feb 25. doi: 10.4049/jimmunol.2100671. Online ahead of print.
- Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies. Gela A, Murphy M, Rodo M, Hadley K, Hanekom WA, Boom WH, Johnson JL, Hoft DF, Joosten SA, Ottenhoff THM, Suliman S, Moody DB, Lewinsohn DM, Hatherill M, Seshadri C, Nemes E, Scriba TJ, Briel L, Veldtsman H, Khomba N, Pienaar B, Africa H, Steyn M; Delayed BCG Study Team. EBioMedicine. 2022 Feb 8. doi: 10.1016/j.ebiom.2022.103839. Online ahead of print.